By Icon Health Publications
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Extra resources for Cleft Lip - A Medical Dictionary, Bibliography, and Annotated Research Guide to Internet References
In sum, these experiments should identify new genes involved in orofacial clefting, advance our understanding of the developmental mechanisms involved, integrate the genes into developmental and molecular pathways, and reveal how these loci interact genetically to contribute to orofacial clefting. Generate_Screen • Project Title: GENETIC BASIS OF CLEFT LIP AND PALATE Principal Investigator & Institution: Jiang, Rulang; Assistant Professor; Eastman Dentistry; University of Rochester Orpa - Rc Box 270140 Rochester, Ny 14627 Timing: Fiscal Year 2003; Project Start 01-APR-2003; Project End 31-MAR-2007 Summary: (provided by applicant): The long-term goal of the proposed research is to understand the molecular pathogenic mechanisms underlying facial cleft formation.
Author(s): Reeve ME, Groce NE, Persing JA, Magge SN. Source: The Journal of Craniofacial Surgery. 2004 January; 15(1): 170-4. cmd=Retrieve&db=pubmed&dopt=A bstract&list_uids=14704585 • Analgesia for cleft lip and palate: comment on Takemura et al. Author(s): Castilla M. Source: Paediatric Anaesthesia. 2003 September; 13(7): 646; Author Reply 647. cmd=Retrieve&db=pubmed&dopt=A bstract&list_uids=12950882 36 Cleft Lip • Analysis of nasal and labial deformities in cleft lip, alveolus and palate patients by a new rating scale: preliminary report.
In addition, a sample of controls with no known family history of clefting will be evaluated for the same phenotypic features in order to compare to the unaffected relatives (of cleft individuals). DNA will be obtained from all study participants in order to investigate a 28 Cleft Lip number of loci that have shown linkage and/or association with CL/P in other studies. These loci are located in specific regions of chromosomes 1, 2, 4, 6, 17 and 19. ; Surgery; Indiana Univ-Purdue Univ at Indianapolis 620 Union Drive, Room 618 Indianapolis, in 462025167 Timing: Fiscal Year 2002; Project Start 01-SEP-2002; Project End 31-MAY-2004 Summary: (provided by applicant): This clinical trial planning grant is to design a multicenter, multi-disciplinary prospectively randomized trial to evaluate the outcomes following two cleft palate repair techniques--Furlow double-Z palatoplasty (Double Z) and intra-velar veloplasty (IVV).
Cleft Lip - A Medical Dictionary, Bibliography, and Annotated Research Guide to Internet References by Icon Health Publications