By Arun D. Singh, Bertil E. Damato, Jacob Pe’er, A. Linn Murphree, Julian David Perry
Written through across the world popular specialists, this ebook offers professional advice and suggestion at the prognosis and administration of the whole diversity of ocular cancers―including eyelid, conjunctival, intraocular, and orbital tumors. From simple ideas throughout the analysis and administration of each melanoma style, it equips you with the cutting-edge wisdom you want to determine those cancers early and deal with them as successfully as attainable. greater than 800 full-color photos and illustrations facilitate analysis, and a constant, basic structure expedites reference. Plus, an advantage CD-ROM permits you to comprise any of the book's figures into your PowerPoint® presentations!
- Provide powerful sufferer care utilizing the newest wisdom on all points of ophthalmic oncology, from uncomplicated rules via medical positive factors, pathology and diagnostic imaging findings, analysis, and differential prognosis, in addition to cutting-edge complete variety of administration options.
- Verify your diagnostic conclusions via evaluating your findings to greater than 800 medical photos from the authors' deepest collections, histopathologic microphotographs, imaging experiences, and crisp illustrations.
- Locate the knowledge you would like quick because of a realistic, clinically concentrated format.
- Gain a world viewpoint of medical perform with enter from 124 authors from 18 countries.
- Enhance your PowerPoint® shows with the bonus photograph library on CD-ROM.
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Additional info for Clinical Ophthalmic Oncology
Kujala E, Makitie T, Kivela T. Very long-term prognosis of patients with malignant uveal melanoma. Invest Ophthalmol Vis Sci 2003; 44: 4651–4659. 79. O’Reilly MS. Angiostatin: an endogenous inhibitor of angiogenesis and of tumor growth. Exs 1997; 79: 273–294. 80. O’Reilly MS, Boehm T, Shing Y et al. Endostatin: an endogenous inhibitor of angiogenesis and tumor growth. Cell 1997; 88: 277–285. 81. O’Reilly MS, Holmgren L, Shing Y et al. Angiostatin: a novel angiogenesis inhibitor that mediates the suppression of metastases by a Lewis lung carcinoma.
Surgical excision with 2–3 mm margins has been the preferred approach for localized disease. 5 mL) followed by interferon drops CONCLUSIONS SECTION 1 Basic principles A B C D Fig. 6 Retinal capillary hemangioma. Ophthalmoscopic appearance of a large hemangioma with retinal exudation and detachment (A). Note prominent feeder vessels (B). Fluorescein angiogram initially ﬁlls the supplying artery (C) and the draining vein ﬂuoresces a few seconds later (D). (1 million U/mL) four times a day for a month after clinical resolution.
Anti-uveal melanoma T-cell responses Although the leukocyte migration assay is no longer used owing to the availability of elegant CTL tests, the ﬁrst data on anti-tumor cellular immune responses in patients were obtained with this test. 18,20 However, the effect of anti-tumor antibodies has only a limited effect on uveal melanoma cells, as immunohistochemical examination of sections of primary uveal melanoma has shown the expression of several complement inhibitors. 21 Inducing anti-tumor immune responses That immune responses may have clinical relevance was shown by a description of one speciﬁc case,22 where repeated injections of an experimental melanoma vaccine led to the shrinkage of an intraocular melanoma.
Clinical Ophthalmic Oncology by Arun D. Singh, Bertil E. Damato, Jacob Pe’er, A. Linn Murphree, Julian David Perry